Yohimbe – Medicinal Uses, Interactions, Side Effects, Dosage
Yohimbe
Yohim be is the crude herbal product derived from the dried bark of Pausinystalia yohimbe, a West African evergreen tree. Yohim bine is the active chemical isolated from yohimbe, also found in smaller concentrations in the root of Rauwolfia.
Uses and Benefits:
Yohimbe bark was originally used in Africa as an aphrodisiac and to restore erections in impotent men. Crude yohimbe and the isolated chemical yohimbine are similarly used in Western countries to increase sexual desire and for erectile dysfunction. These products are also used in male “performance” supplements, and for fatigue, orthostatic hypotension, obesity, and clonidine overdose.
Pharmacology:
The bark of P. yohimbe contains up to 6% mixed indole alkaloids, of which yohimbine is the principal active constituent. Structurally related to reserpine, yohimbine has been well characterized as a selective alpha adrenergic receptor antago
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